Cardiothoracic & vascular anesthesia
Comparison of Intraoperative Blood Product Use During Heart Transplantation in Patients Bridged with Impella 5.5 versus Durable Left Ventricular Assist Devices
Authors' conclusion
The results suggest a reduction in certain intraoperative transfusion requirements in patients undergoing heart transplantation bridged with the Impella 5.5 versus durable left ventricular assist device.
Study context
- Population
- Adults bridged to heart or heart/kidney transplantation with a temporary or durable left ventricular assist device (LVAD), tertiary care hospital, 2018–2021
- Participants
- 43 adults
- Exposure
- Impella 5.5 vs durable LVAD as bridge to heart transplantation
- Outcome
- Volume of blood products transfused intraoperatively
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Impella 5.5
- median cryoprecipitate 155 mL versus 200 mL; P = 0.015
- Impella 5.5
- median autologous blood salvage 675 mL versus 1,125 mL; P ≤ 0.01
- Impella 5.5
- median platelets 412 mL versus 675 mL; P ≤ 0.01
- Not statistically significant
- packed RBC 4.5 units versus 6.5 units; P = 0.29
- Not statistically significant
- FFP 675 mL versus 800 mL; P = 0.11
Observational data: associations, not effects.
Original publication
Comparison of Intraoperative Blood Product Use During Heart Transplantation in Patients Bridged with Impella 5.5 versus Durable Left Ventricular Assist Devices. J Cardiothorac Vasc Anesth. Published 6 May 2024. doi:10.
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