Respiratory failure & ventilation
Comparison of the novel membrane-based carbon dioxide filter memsorb™ with a chemical granulate absorbent using a high-fidelity lung simulator: a prospective randomized in vitro trial
Authors' conclusion
CO2 was successfully removed from the anesthesia circuit. FICO2 was significantly higher with memsorb throughout the observation period.
Study context
- Population
- In vitro lung simulator (DUCt) imitating alveolar gas exchange; no patients3 trials per fresh gas flow (FGF) per device
- Comparison
- Memsorb vs chemical granulate absorber (CGA)
Methodological detailsprospective, high-fidelity lung simulator
- Prospective
- High-fidelity lung simulator
Primary result
As reported in the abstract
EtCO2 and FICO2 over 30 min · 30 min
memsorb vs CGADifference, mm Hg (95% CI)P value
EtCO2, FGF 0.5 L·min-1
3.7(2.7–4.7)
P = 0.004- FICO2, FGF 2 L·min-1
- difference 3.9 mm Hg (95% CI 4.4–3.3); P < 0.001
- FICO2, FGF 0.5 L·min-1
- difference 6 mm Hg (95% CI 6.4–5.5); P < 0.001
Original publication
Comparison of the novel membrane-based carbon dioxide filter memsorb™ with a chemical granulate absorbent using a high-fidelity lung simulator: a prospective randomized in vitro trial. Can J Anaesth. Published 11 September 2023. doi:10. 1007/ s12630-023-02563-7
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