Respiratory failure & ventilation

Comparison of the novel membrane-based carbon dioxide filter memsorb™ with a chemical granulate absorbent using a high-fidelity lung simulator: a prospective randomized in vitro trial

Can J AnaesthPublished Randomised in vitro trial

Authors' conclusion

CO2 was successfully removed from the anesthesia circuit. FICO2 was significantly higher with memsorb throughout the observation period.

Study context

Population
In vitro lung simulator (DUCt) imitating alveolar gas exchange; no patients3 trials per fresh gas flow (FGF) per device
Comparison
Memsorb vs chemical granulate absorber (CGA)
Methodological detailsprospective, high-fidelity lung simulator
  • Prospective
  • High-fidelity lung simulator

Primary result

As reported in the abstract

EtCO2 and FICO2 over 30 min · 30 min
memsorb vs CGADifference, mm Hg (95% CI)P value
EtCO2, FGF 0.5 L·min-1
3.7(2.7–4.7)
P = 0.004
FICO2, FGF 2 L·min-1
difference 3.9 mm Hg (95% CI 4.4–3.3); P < 0.001
FICO2, FGF 0.5 L·min-1
difference 6 mm Hg (95% CI 6.4–5.5); P < 0.001

Original publication

Comparison of the novel membrane-based carbon dioxide filter memsorb™ with a chemical granulate absorbent using a high-fidelity lung simulator: a prospective randomized in vitro trial. Can J Anaesth. Published 11 September 2023. doi:10.1007/s12630-023-02563-7

Composed by AI from the published abstract and checked against it. How Briefs are made →

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