Cardiothoracic & vascular anesthesia
Comparison of Arterial Partial Pressure of Carbon Dioxide with That at Oxygenator Exhaust During Cardiopulmonary Bypass for Pediatric Cardiac Surgery
Authors' conclusion
Under stable mild hypothermic CPB conditions, PeCO₂ demonstrates a strong correlation with temperature-corrected PaCO₂ and can be predicted using a simple linear equation in pediatric patients undergoing elective cardiac surgery.
Study context
- Population
- Children aged 1–12 years undergoing elective cardiac surgery for biventricular repair with stable mild hypothermic cardiopulmonary bypass (CPB) (membrane oxygenator), tertiary care hospital80 paired measurements
- Participants
- 40 children
- Exposure
- Oxygenator exhaust PeCO₂ vs temperature-corrected PaCO₂
- Outcome
- Agreement between PeCO₂ and temperature-corrected PaCO₂ (Bland-Altman analysis)
Methodological detailsmethod-agreement (Bland-Altman analysis)
- Method-agreement (Bland-Altman analysis)
Main finding
As reported in the abstract
Agreement of PeCO₂ with temperature-corrected PaCO₂
Correlation coefficient
0.81
Bias
0.036
SD
2.76
Limits of agreement
−5.37 to 5.44
Observational data: associations, not effects.
Further findings
Correlation of PeCO₂ with temperature-uncorrected PaCO₂
- No significant correlation
Original publication
Comparison of Arterial Partial Pressure of Carbon Dioxide with That at Oxygenator Exhaust During Cardiopulmonary Bypass for Pediatric Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 25 October 2025. doi:10.
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