Cardiothoracic & vascular anesthesia

A comparison of the NeurOs® and the INVOS 5100C® cerebral oximeter during variations of the partial pressure of carbon dioxide and fractional inspiratory concentration of oxygen

J Clin Monit ComputPublished Method comparison study

Authors' conclusion

The ScO2 measurement performance of the NeurOs® cerebral oximeter is not interchangeable with the INVOS® cerebral oximeter during variations of ventilation and oxygenation in elective cardiac or vascular surgical patients.

Study context

Population
Anesthetized cardiac and vascular surgical patients during hemodynamically stable conditionspooled data
Participants
59 participants
Exposure
NeurOs® vs INVOS 5100C® cerebral oximeter
Outcome
Agreement of ScO2 measurement (Bland-Altman bias and limits of agreement) during variations of PaCO2 and of SaO2 by FiO2
Methodological detailsprospective
  • Prospective

Main finding

As reported in the abstract

Bias, PaCO2 variation
- 0.5%
Lower limit of agreement, PaCO2 variation (95% CI - 19.6 to - 13.7%)
- 16.3%
Upper limit of agreement, PaCO2 variation
15.4% (95% CI 12.8 to 18.8%)
Bias, saturation (SaO2) variation by fraction of oxygen (FiO2)
- 0.8%
Lower limit of agreement, SaO2 variation (95% CI - 19.7 to - 13.6%)
- 16.3%
Upper limit of agreement, SaO2 variation
14.7% (95% CI 12.1 to 18.2%)

Observational data: associations, not effects.

Further findings

Baseline agreement by NeurOs® sensor version

Comparable bias and limits of agreement with bi-hemispherical sensor and two-sensor version

ScO2 in default vs high penetration mode (newer NeurOs® version)

No significant differences in ScO2

Original publication

A comparison of the NeurOs® and the INVOS 5100C® cerebral oximeter during variations of the partial pressure of carbon dioxide and fractional inspiratory concentration of oxygen. J Clin Monit Comput. Published 6 January 2023. doi:10.1007/s10877-022-00963-6

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