Anesthetic drugs & techniques

Comparison of Contralateral Acceleromyography and Electromyography for Posttetanic Count Measurement

AnesthesiologyPublished Method-comparison study

Authors' conclusion

Acceleromyography frequently counted more twitches than electromyography in posttetanic count monitoring. Acceleromyography- and electromyography-posttetanic counts cannot be used interchangeably to assess the degree of neuromuscular blockade.

Study context

Population
Patients aged 20 to 65 yr given rocuronium 0.6 mg/kg (additional 0.3 mg/kg if required)226 measurement pairs analysed
Participants
36 patients
Comparison
Acceleromyography vs electromyography for posttetanic count
Outcome
Agreement of NMB status (intense block, posttetanic count 0; deep block, posttetanic count ≥1 and TOF count 0) and of posttetanic count between acceleromyography and electromyography
Methodological detailscontralateral arm monitoring, Posttetanic count measured at 6-min intervals until TOF count reached 1
  • Contralateral arm monitoring
  • Posttetanic count measured at 6-min intervals until TOF count reached 1

Main finding

As reported in the abstract

Agreement of NMB status (intense or deep block)

Percentage agreement of NMB status

73%

Cohen's kappa

0.26

Further findings

OutcomeDifference in mean posttetanic count (lower) (%) (95% CI)P value
Agreement of posttetanic count (acceleromyography-posttetanic counts >15 excluded; 184 pairs)38 (20–51%)P = 0.0002
Agreement of posttetanic count (acceleromyography-posttetanic counts >15 excluded; 184 pairs) — Pairs with same acceleromyography and electromyography posttetanic count
42 (23%)
Agreement of posttetanic count (acceleromyography-posttetanic counts >15 excluded; 184 pairs) — Pairs with acceleromyography count more than electromyography count
93 (50%)

Original publication

Comparison of Contralateral Acceleromyography and Electromyography for Posttetanic Count Measurement. Anesthesiology. Published 15 December 2022. doi:10.1097/aln.0000000000004466

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.