Comparison of Outcomes in Patients Requiring Mechanical Circulatory Support Who Received Cangrelor in Addition to Anticoagulation Versus Anticoagulation Alone
Main findingResult — go to the resultAdjusted hazard ratio 1.93 95% CI 0.61–6.11Authors' conclusion
Patients receiving cangrelor did not appear to be at higher risk of major bleeding compared to patients not receiving cangrelor.
Study context
- Population
- Adults in the cardiovascular ICU on mechanical circulatory support for acute MI or non-MI indications, tertiary medical center, January 2016–October 2020
- Participants
- 68 adults
- Exposure
- Cangrelor plus anticoagulation vs no cangrelor
- Cangrelorn = 29
- No cangrelorn = 39reference
- Outcome
- Major bleeding (Extracorporeal Life Support Organization criteria)
Methodological detailssingle-center
- Single-center
Main finding
As reported in the abstract
Adjusted hazard ratio
1.93
95% CI 0.61–6.11
P = 0.262
Cangrelor vs No cangrelor
aHR 1.93 (95% CI 0.61–6.11); P = 0.262
Observational data: associations, not effects.
Original publication
Comparison of Outcomes in Patients Requiring Mechanical Circulatory Support Who Received Cangrelor in Addition to Anticoagulation Versus Anticoagulation Alone. J Cardiothorac Vasc Anesth. Published 2 March 2024. doi:10.
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