Pediatric anesthesia & critical care
Comparison of postoperative pain in children after maintenance anaesthesia with propofol or sevoflurane: a systematic review and meta-analysis
Pooled result · Overall postoperative painResult — go to the resultOdds ratio 1.88 95% CI 1.12–3.15Authors' conclusion
Children maintained on inhalational sevoflurane had higher odds of postoperative pain compared with those maintained on propofol.
Study context
- Population
- Children undergoing paediatric surgery
- Participants
- 1,174 children · 13 randomised controlled trials (RCTs)
- Comparison
- Sevoflurane vs propofol for maintenance of anaesthesia
- Outcome
- Overall postoperative pain
Methodological detailsbias-adjusted inverse heterogeneity methods
- Bias-adjusted inverse heterogeneity methods
Pooled result
As reported in the abstract
Odds ratio
1.88
95% CI 1.12–3.15
Sevoflurane vs Propofol
OR 1.88 (95% CI 1.12–3.15)
Further pooled results
| Outcome | OR (95% CI) | |
|---|---|---|
| Higher pain scoresI2=20.9% | 3.18 (1.83–5.53) | |
| Postoperative rescue analgesiaI2=58.2% | 1.60 (0.89–2.88) | |
| 0.20.5125Odds ratio (log scale) |
Original publication
Comparison of postoperative pain in children after maintenance anaesthesia with propofol or sevoflurane: a systematic review and meta-analysis. Br J Anaesth. Published 26 April 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →