Pediatric anesthesia & critical care
Propofol Versus Sevoflurane Anesthesia for Acute Postoperative Pain Management in Pediatric Adenotonsillectomy: A Randomized Controlled Trial
An erratum to this article was published (Paediatr Anaesth, Jan 2026 ↗)
Primary resultResult — go to the resultOdds ratio 0.78 95% CI 0.28–2.18Authors' conclusion
The incidence and intensity of acute postoperative pain in the first 24 h after adenotonsillectomy did not differ significantly between pediatric patients who received maintenance anesthesia with propofol or with sevoflurane.
Study context
- Population
- Children aged 2–7 years undergoing adenotonsillectomy142 completed
- Participants
- 144 children
- Comparison
- Propofol vs sevoflurane maintenance anaesthesia
- Propofoln = 71
- Sevofluranen = 71reference
- Primary endpoint
- Proportion with acute postoperative pain, Face, Legs, Activity, Cry, and Consolability (FLACC) scale scores > 3
- Follow-up
- Within 24 h
Methodological detailssingle-blind
- Single-blind
Primary result
As reported in the abstract
Odds ratio
0.78
95% CI 0.28–2.18
P = 0.500
Events by treatment group
Propofol vs Sevoflurane
OR 0.78 (95% CI 0.28–2.18); P = 0.500
Secondary outcomes
| Outcome | Estimate |
|---|---|
| Pain scores (NRS at activity, PPPM) · postoperative days 2-3Propofol vs Sevoflurane · below MCID threshold (ΔNRS > 1) | median difference (ΔNRS at activity) 1 |
| Pain scores (NRS at activity, PPPM) · postoperative days 2-3Propofol vs Sevoflurane · below MCID threshold (ΔPPPM > 3) | median difference (ΔPPPM) 1 |
Pain scores (numeric rating scale (NRS) at activity, parent's postoperative pain measure (PPPM)) · postoperative days 2-3
- Higher pain scores in the Propofol group
Original publication
Propofol Versus Sevoflurane Anesthesia for Acute Postoperative Pain Management in Pediatric Adenotonsillectomy: A Randomized Controlled Trial. Paediatr Anaesth. Published 8 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →