Hemodynamics, fluids & transfusion
Comparison of the Incidence of Arterial Pressure Line Insufficiency Between Polyethylene and Polyurethane Catheters in the ICU: A Randomized Study
Primary resultResult — go to the resultRelative risk 0.15 95% CI 0.05–0.48- early termination
- Trial terminated early after interim analysis of 132 patients
Authors' conclusion
This study demonstrated a lower occurrence rate of arterial line insufficiency with polyethylene arterial catheters than polyurethane catheters.
Study context
- Population
- Adults scheduled for elective cardiovascular surgery with postoperative ICU admission, cardiovascular center in Japaninterim analysis
- Participants
- 132 adults
- Comparison
- Polyethylene vs polyurethane arterial catheters
- Polyethylenen = 69
- Polyurethanen = 63reference
- Primary endpoint
- Arterial line insufficiency (≥1 of: flattened/overdamped BP waveform, sluggish free backflow >2 s, inability to draw blood, inability to flush)
- Follow-up
- First noon after ICU admission
Methodological detailsdouble-blinded, superiority, single-centre, interim analysis
- Double-blinded
- Superiority
- Single-centre
- Interim analysis
Primary result
As reported in the abstract
Relative risk
0.15
95% CI 0.05–0.48
P = 0.001
Events by treatment group
Polyethylene vs Polyurethane
RR 0.15 (95% CI 0.05–0.48); P = 0.001
Original publication
Comparison of the Incidence of Arterial Pressure Line Insufficiency Between Polyethylene and Polyurethane Catheters in the ICU: A Randomized Study. Crit Care Med. Published 16 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →