Organ support & nutrition

Current Use and Impact of Pulmonary Artery Catheters on the Short-Term Outcomes in Patients With Cardiogenic Shock Treated With an Impella: Findings From the Japan Registry for Percutaneous Ventricular Assist Device (J-PVAD)

Crit Care MedPublished Prospective multicentre observational study

Authors' conclusion

The J-PVAD findings indicated that PAC use did not have a significant impact on the short-term outcomes in CS patients undergoing Impella support.

Study context

Population
Patients with cardiogenic shock treated with an Impella (2.5, CP or 5.0), cardiac ICUs in Japan, J-PVAD registry, January 2020–December 2021Cardiogenic shock (CS) patients of 3112 enrolled
Participants
2,063 patients
Exposure
PAC use vs no PAC use
  • Pulmonary artery catheters (PACs)n = 1,358
Outcome
30-day mortality
Follow-up
30 days
Methodological detailsregistry
  • Registry

Main finding

As reported in the abstract

  • 30-day mortality did not significantly differ according to PAC use

Observational data: associations, not effects.

Secondary outcomes

Hemolysis, AKI, sepsis, major bleeding unrelated to the Impella, ventricular arrhythmias · within 30 days

Did not significantly differ according to PAC use

Venoarterial extracorporeal membrane oxygenation (VA-ECMO) use

Significantly higher with PACs than without

30-day mortality and hemolysis (VA-ECMO subgroup)

Univariately lower with PACs
  • Univariate

Original publication

Current Use and Impact of Pulmonary Artery Catheters on the Short-Term Outcomes in Patients With Cardiogenic Shock Treated With an Impella: Findings From the Japan Registry for Percutaneous Ventricular Assist Device (J-PVAD). Crit Care Med. Published 9 February 2024. doi:10.1097/ccm.0000000000006225

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