Anesthetic drugs & techniques

Connected consciousness after tracheal intubation in young adults: an international multicentre cohort study

Br J AnaesthPublished Prospective cohort study

Authors' conclusion

Connected consciousness occured after intubation in 11% of young adults, with females at increased risk.

Study context

Population
Young people aged 18–40 yr undergoing GA with tracheal intubation338 completed
Participants
344 people
Outcome
Incidence of connected consciousness (response to command, isolated forearm technique) after tracheal intubation
Follow-up
Shortly after tracheal intubation
Methodological detailsinternational, multicentre, isolated forearm technique
  • International
  • Multicentre
  • Isolated forearm technique

Main finding

As reported in the abstract

Connected consciousness (response to command) after tracheal intubation

Responses after intubation

37/338 subjects

11%

Observational data: associations, not effects.

Secondary outcomes

Responsiveness by sex

ValuesaOR (95% CI)P value
Female sexLogistic regressionFemales 13% · Males 6%2.7 (1.1–7.6)P = 0.022

Responsiveness with continuous anaesthesia before laryngoscopy

aOR (95% CI)P value
Continuous anaesthesia before laryngoscopyLogistic regression0.43 (0.20–0.96)P = 0.041
OutcomeValuesP value
Nature of responses: to command only vs to nonsense onlyCommand only 13 events · Nonsense only 4 eventsP = 0.049

Nature of responses: to command only vs to nonsense only

Responses more likely after a command than after a nonsense statement

Original publication

Connected consciousness after tracheal intubation in young adults: an international multicentre cohort study. Br J Anaesth. Published 23 May 2022. doi:10.1016/j.bja.2022.04.010

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