Anesthetic drugs & techniques

Evaluation of putative signatures of consciousness using specific definitions of responsiveness, connectedness, and consciousness

Br J AnaesthPublished Secondary analysis of the UNderstanding Consciousness Connectedness and Intra-Operative Unresponsiveness Study

Authors' conclusion

None of the proposed EEG-based neural correlates of unresponsiveness corresponded solely to consciousness, highlighting the need for a more conservative use of the term (un)consciousness when assessing unresponsive participants.

Study context

Population
Unresponsive subjects during dexmedetomidine or propofol sedation or natural sleep
Comparison
Resting-state EEG measures across connected consciousness, disconnected consciousness and unconsciousness

Primary result

As reported in the abstract

Association of 10 published resting-state EEG measures with consciousness vs connectedness
Disconnected consciousness to unconsciousness: significant decreases in permutation entropy and spectral exponent
P<0.05

Original publication

Evaluation of putative signatures of consciousness using specific definitions of responsiveness, connectedness, and consciousness. Br J Anaesth. Published 31 October 2023. doi:10.1016/j.bja.2023.09.031

Composed by AI from the published abstract and checked against it. How Briefs are made →

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