Perioperative medicine & outcomes

Critical Care Therapy After Cytoreductive Nephrectomy for Metastatic Kidney Cancer

Crit Care MedPublished Retrospective cohort study

Authors' conclusion

After cytoreductive nephrectomy, critical care therapy rate was 7.3% vs. in-hospital mortality was 2.4%. Of patients at highest risk of critical care therapy need were those with CCI greater than or equal to 3 and those 71 years old or older.

Study context

Population
Surgically treated metastatic kidney cancer patients undergoing cytoreductive nephrectomy
Participants
10,915 participants
Outcome
Critical care therapy
Methodological detailsNational Inpatient Sample (2000-2019), multivariable logistic regression, estimated annual percentage changes
  • National Inpatient Sample (2000-2019)
  • Multivariable logistic regression
  • Estimated annual percentage changes

Main finding

As reported in the abstract

Patients receiving critical care therapy
802 (7.3%)
Critical care therapy rate, 2000 to 2019 (no significant change, p = 0.07)
6.6% to 5.7%
Age ≥71 y predicting critical care therapy (OR; p < 0.001)
1.43
CCI ≥ 3 predicting critical care therapy (OR; p < 0.001)
2.92
CCI 1-2 predicting critical care therapy (OR; p < 0.001)
1.45
Partial nephrectomy predicting critical care therapy (OR; p = 0.003)
0.51
Minimally invasive surgery predicting critical care therapy (OR; p < 0.001)
0.33

Observational data: associations, not effects.

Further findings

In-hospital deaths
249 (2.4%)
In-hospital mortality decreased over time (p = 0.004)
2.3% to 1.9%
Virtually the same predictor associations as for critical care therapy

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Critical Care Therapy After Cytoreductive Nephrectomy for Metastatic Kidney Cancer. Crit Care Med. Published 14 November 2024. doi:10.1097/ccm.0000000000006496

Composed by AI from the published abstract and checked against it. How Briefs are made →

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