Perioperative medicine & outcomes
Critical Care Therapy After Cytoreductive Nephrectomy for Metastatic Kidney Cancer
Authors' conclusion
After cytoreductive nephrectomy, critical care therapy rate was 7.3% vs. in-hospital mortality was 2.4%. Of patients at highest risk of critical care therapy need were those with CCI greater than or equal to 3 and those 71 years old or older.
Study context
- Population
- Surgically treated metastatic kidney cancer patients undergoing cytoreductive nephrectomy
- Participants
- 10,915 participants
- Outcome
- Critical care therapy
Methodological detailsNational Inpatient Sample (2000-2019), multivariable logistic regression, estimated annual percentage changes
- National Inpatient Sample (2000-2019)
- Multivariable logistic regression
- Estimated annual percentage changes
Main finding
As reported in the abstract
- Patients receiving critical care therapy
- 802 (7.3%)
- Critical care therapy rate, 2000 to 2019 (no significant change, p = 0.07)
- 6.6% to 5.7%
- Age ≥71 y predicting critical care therapy (OR; p < 0.001)
- 1.43
- CCI ≥ 3 predicting critical care therapy (OR; p < 0.001)
- 2.92
- CCI 1-2 predicting critical care therapy (OR; p < 0.001)
- 1.45
- Partial nephrectomy predicting critical care therapy (OR; p = 0.003)
- 0.51
- Minimally invasive surgery predicting critical care therapy (OR; p < 0.001)
- 0.33
Observational data: associations, not effects.
Further findings
- In-hospital deaths
- 249 (2.4%)
- In-hospital mortality decreased over time (p = 0.004)
- 2.3% to 1.9%
- Virtually the same predictor associations as for critical care therapy
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Critical Care Therapy After Cytoreductive Nephrectomy for Metastatic Kidney Cancer. Crit Care Med. Published 14 November 2024. doi:10. 1097/ ccm. 0000000000006496
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