Organ support & nutrition

Current concepts on feeding the critically ill patient: a narrative review

Crit CarePublished Narrative review

Authors' conclusion

Integrating individualised energy and protein prescription, targeted micronutrient management, emerging metabolic therapies, and coordinated post-ICU rehabilitation may optimise recovery and functional outcomes.

Study context

Population
Critically ill ICU patients, through critical illness, post-ICU and outpatient recovery
Methodological detailsexpert review (39th Annual Conference of the German Society for Nutritional Medicine, DGEM)
  • Expert review (39th Annual Conference of the German Society for Nutritional Medicine, DGEM)

Main finding

As reported in the abstract

  • Inflammation and high disease severity strongly influence nutritional responsiveness; highly inflamed patients show reduced benefit and higher overfeeding risk
  • Personalised strategies (indirect calorimetry, fat-free mass-based protein dosing, metabolic biomarkers such as urea-creatinine ratio) offer a rational framework for tailoring therapy
  • Micronutrient deficiencies common (redistribution, pre-existing deficits, extracorporeal losses), needing structured assessment and supplementation
  • Macronutrient delivery should be progressively escalated, as a pharmacologic intervention aligned with disease phase and organ function
  • Early standardised ketogenic diet protocols show feasibility and potential clinical benefit in refractory status epilepticus and sepsis
  • Post-ICU and outpatient phases remain nutritionally vulnerable (persistent catabolism, underfeeding common); structured multidisciplinary rehabilitation and transitional nutrition programs may improve long-term outcomes
  • Not exhaustive; interpretations partly reflect the experts' views

Original publication

Current concepts on feeding the critically ill patient: a narrative review. Crit Care. Published 12 June 2026. doi:10.1186/s13054-026-06123-5

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