Respiratory failure & ventilation
Defining and subphenotyping acute respiratory distress syndrome (ARDS): insights from an international Delphi expert panel
Authors' conclusion
The findings underscore the need to refine the ARDS definition to better account for the heterogeneity of clinical presentations and underlying pathophysiology, and to improve diagnostic precision, including the use of subphenotyping where appropriate.
Study context
- Population
- Experts in ARDS research and management from diverse geoeconomic regions and professional backgrounds
- Outcome
- Consensus on the conceptual model of ARDS, its defining components for clinical, research and educational contexts, and the role of subphenotyping
Methodological detailsPosition Paper, four-round Delphi, international expert panel, panellist anonymity, quantitative consensus criteria, Four Delphi rounds; panellist anonymity and clear quantitative criteria used to mitigate peer pressure and group conformity
- Position Paper
- Four-round Delphi
- International expert panel
- Panellist anonymity
- Quantitative consensus criteria
- Four Delphi rounds; panellist anonymity and clear quantitative criteria used to mitigate peer pressure and group conformity
Recommendations
As reported in the abstract
- Consensus achieved for the conceptual model of ARDS
- Consensus achieved on key components of an ARDS definition for research, education and patient management
- Consensus achieved on the need for further research in subphenotyping ARDS
Further findings
- Knowledge gaps and research priorities highlighted to guide future investigations
Original publication
Defining and subphenotyping ARDS: insights from an international Delphi expert panel. Lancet Respir Med. Published 29 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →