Respiratory failure & ventilation
Defining the Resolution of Acute Respiratory Distress Syndrome: A Delphi Consensus Study
Authors' conclusion
A high level of consensus was achieved on criteria defining the resolution of ARDS.
Study context
- Population
- Panel of acute respiratory distress syndrome (ARDS) experts identified using prespecified criteria16 contributed to final definition
- Participants
- 19 participants
- Outcome
- Consensus elements of ARDS resolution
- Follow-up
- After the third round
Methodological detailsthree iterative rounds, electronic surveys, a priori agreement threshold 70%
- Three iterative rounds
- Electronic surveys
- A priori agreement threshold 70%
Recommendations
As reported in the abstract
- Resolution of hypoxemia: PaO2/FiO2 >300 (or SpO2/FiO2 >315) for >24 hours
- Normalization of respiratory support: if intubated, primarily for nonrespiratory reasons with minimal ventilatory assistance (PEEP ≤5 cm H2O, no adjunctive interventions); if maximal support was continuous positive airway pressure (CPAP) or noninvasive ventilation (NIV), no longer requiring CPAP or NIV; if high-flow nasal cannula (HFNC), no longer requiring HFNC; if standard oxygen, no longer receiving oxygen
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Defining the Resolution of Acute Respiratory Distress Syndrome: A Delphi Consensus Study. Crit Care Med. Published 2 April 2026. doi:10.
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