Depth of anaesthesia and mortality after cardiac or noncardiac surgery: a systematic review and meta-analysis of randomised controlled trials
Pooled result · Mortality, all studies pooledResult — go to the resultOdds ratio 0.99 95% CI 0.92–1.08Authors' conclusion
pEEG-guided lighter anaesthesia does not appear to reduce the risk of postoperative mortality.
Study context
- Population
- Adults aged ≥18 yr undergoing cardiac or noncardiac surgery in RCTs of processed electroencephalography (pEEG) monitoring
- Participants
- 48,827 adults · 12 RCTs
- Comparison
- pEEG-guided light vs deep anaesthesia
- Outcome
- Mortality (30 days, 90 days and/or 1 yr or longer)
Methodological detailsPRISMA
- PRISMA
Pooled result
Mortality, all studies pooled
Odds ratio
0.99
95% CI 0.92–1.08
Light anaesthesia vs Deep anaesthesia
OR 0.99 (95% CI 0.92–1.08)
As reported in the abstract
Further pooled results
| Outcome | OR (95% CI) | |
|---|---|---|
| Mortality, pEEG monitoring vs usual care | 1.02 (0.89–1.18) | |
| Mortality, higher vs lower pEEG index targets | 0.89 (0.60–1.32) | |
| Mortality, low pEEG index value alerts vs no alerts | 1.02 (0.41–2.52) | |
| 0.20.5125Odds ratio (log scale) |
Mortality at 30 days, 90 days, 1 yr or longer
- Result did not change significantly
Original publication
Depth of anaesthesia and mortality after cardiac or noncardiac surgery: a systematic review and meta-analysis of randomised controlled trials. Br J Anaesth. Published 7 October 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →