Airway management

Detection of cocaine 24 h after administration before nasotracheal intubation

Acta Anaesthesiol ScandPublished Prospective study

Authors' conclusion

We found benzoylecgonine traceable in saliva in 13% of patients and cocaine traceable in blood in 3% of patients 24 h after administration of 80 mg nasal cocaine.

Study context

Population
Patients scheduled for surgery under GA with nasotracheal intubation70 valid saliva samples
Outcome
Benzoylecgonine in saliva above cut-off 200 ng/mL (dichotomous)
Follow-up
24 h after administration

Main finding

As reported in the abstract

Benzoylecgonine in saliva above cut-off (200 ng/mL)

Benzoylecgonine in saliva traceable above cut-off

9/70 patients

13%; CI95%: 6% to 23%

Observational data: associations, not effects.

Secondary outcomes

Cocaine in blood above cut-off (0.01 mg/kg) · 24 h after administration

Cocaine in blood detected above cut-off
2/75 patients (3%; CI95%: 0.3% to 9%)
  • 75 patients with valid blood samples

Original publication

Detection of cocaine 24 h after administration before nasotracheal intubation. Acta Anaesthesiol Scand. Published 26 June 2024. doi:10.1111/aas.14475

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