Cardiothoracic & vascular anesthesia

Determinants of Length of Intensive Care Unit Stay After Simultaneous Aortic and Mitral Valve Replacement

J Cardiothorac Vasc AnesthPublished Retrospective observational study

Authors' conclusion

Age, preoperative left ventricular ejection fraction, cardiopulmonary bypass time, intraoperative blood product transfusion, intra-aortic balloon pump insertion, ventilation time, occurrence of atrial fibrillation, and positive inotropic agent usage were independent determinants of the length of ICU stay at various proposed stages in patients undergoing simultaneous AVR and MVR.

Study context

Population
Consecutive patients undergoing simultaneous aortic valve replacement (AVR) and mitral valve replacement (MVR), 2006–2020
Participants
395 consecutive patients
Outcome
Length of ICU stay (natural logarithm)
Methodological detailssingle-centre, tertiary referral cardiovascular center, consecutive patients, multivariable analysis
  • Single-centre
  • Tertiary referral cardiovascular center
  • Consecutive patients
  • Multivariable analysis

Main finding

As reported in the abstract

Independent determinants of Ln (length of ICU stay), by stage
  • Before surgery: age independently associated with Ln (length of intensive care unit (ICU) stay)
  • At ICU admission: age, preoperative left ventricular ejection fraction, CPB time, intraoperative blood product transfusion and intra-aortic balloon pump insertion independently correlated
  • During ICU stay: ventilation time, AF, positive inotropic agent use and all the above variables independently associated
  • Multivariable analysis

Observational data: associations, not effects.

Original publication

Determinants of Length of Intensive Care Unit Stay After Simultaneous Aortic and Mitral Valve Replacement. J Cardiothorac Vasc Anesth. Published 21 September 2025. doi:10.1053/j.jvca.2025.09.037

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