Cardiothoracic & vascular anesthesia

Outcomes of Aortomitral Continuity Reconstruction During Concomitant Aortic and Mitral Valve Replacement

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Main finding · Long-term survivalResult — go to the resultHR for death 1.29 95% CI 0.65–2.59

Authors' conclusion

Although short-term postoperative morbidity and mortality were found to be higher for patients undergoing the Commando procedure, AMC reconstruction may be equally durable in the long term.

Study context

Population
Patients undergoing double aortic and mitral valve replacement, single institution, 2010–2022
Participants
331 patients
Exposure
Commando procedure vs mitral valve replacement (MVR) + aortic valve replacement (AVR) without aortomitral continuity (AMC) reconstruction
  • Commandon = 21
Outcome
Long-term survival
Methodological detailssingle institution, consecutive cardiac surgeries
  • Single institution
  • Consecutive cardiac surgeries

Main finding

As reported in the abstract

HR for death

1.29

95% CI 0.65–2.59

P = 0.496

Commando vs MVR + AVR
HR for death 1.29 (95% CI 0.65–2.59); P = 0.496
No difference in long-term survival between groups (Kaplan-Meier, log-rank)
P = 0.386

Observational data: associations, not effects.

Further findings

Operative mortality

Higher in Commando: 28.6% v 10.7%
P = 0.014

CPB time

Longer in Commando: 312 ± 118 v 218 ± 85 minutes
P < 0.001

Prolonged ventilation

More in Commando: 61.9% v 31.9%
P = 0.005

Ischemic time

Longer in Commando: 252 ± 90 v 176 ± 66 minutes
P < 0.001

Safety

Prolonged ventilation

P = 0.005

Original publication

Outcomes of Aortomitral Continuity Reconstruction During Concomitant Aortic and Mitral Valve Replacement. J Cardiothorac Vasc Anesth. Published 17 January 2024. doi:10.1053/j.jvca.2024.01.007

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