Cardiothoracic & vascular anaesthesia

Outcomes of Patients Undergoing Mitral Valve Replacement After Failed Attempt at Mitral Valve Repair

J Cardiothorac Vasc AnesthPublished Retrospective observational study

Authors' conclusion

Postoperative outcomes were similar despite longer operative times in the IR group. Failure of initial MVr, leading to MVR, did not translate into adverse early or long-term outcomes.

Study context

Population
Patients undergoing mitral valve replacement (MVR) 2010–2024, incl. concomitant surgeries; single institutionmean age 64 y
Participants
1,661 patients
Exposure
MVR after failed attempted mitral valve repair (MVr) vs planned MVR
  • Intended repair (IR)n = 133
  • DRn = 1,528reference
Outcome
Perioperative morbidity and mortality
Methodological detailssingle-centre, university affiliated, propensity-score matched
  • Single-centre
  • University affiliated
  • Propensity-score matched

Main finding

As reported in the abstract

  • Similar after propensity score matching
  • Propensity-score matched

Observational data: associations, not effects.

Further findings

CPB time

Cross-clamp time

OutcomeP value
Survival (Kaplan-Meier) · 5 yearsSimilarP = 0.91

Original publication

Outcomes of Patients Undergoing Mitral Valve Replacement After Failed Attempt at Mitral Valve Repair. J Cardiothorac Vasc Anesth. Published 24 August 2026. doi:10.1053/j.jvca.2026.08.146

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