Cardiothoracic & vascular anesthesia
Development and Validation of a Predictive Model for Hypoxemia in the Postanesthesia Care Unit Following Thoracoscopic Lung Surgery: A Multicenter Cohort Study
Authors' conclusion
Seven risk factors were independently associated with hypoxemia in the postanesthesia care unit following thoracoscopic lung surgery.
Study context
- Population
- Adults (≥18 years; ASA I–III) undergoing elective thoracoscopic lung resection, 2 tertiary hospitals in China, January 2020 to January 2022
- Participants
- 2,563 adults
- Exposure
- Nomogram of 7 risk factors for PACU hypoxemia; training vs internal and external validation cohorts
- Trainingn = 1,251
- Internal validationn = 417
- External validationn = 895
- Outcome
- Nomogram discrimination and hypoxemia incidence
Methodological detailsmulticentre, prediction model development and validation, external validation
- Multicentre
- Prediction model development and validation
- External validation
Main finding
As reported in the abstract
| Group | Value | AUC |
|---|---|---|
| Training | 28.38% | 0.841 |
| Internal validation | 0.864 | |
| External validation | 0.812 |
Value
Training28.38%
Internal validation— not stated in the abstract
External validation— not stated in the abstract
AUC
Training0.841
Internal validation0.864
External validation0.812
Observational data: associations, not effects.
Further findings
Decision curve and clinical impact curve analyses
- Superior clinical net benefit over pulse oximetry alone when risk of hypoxemia exceeded 42%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Development and Validation of a Predictive Model for Hypoxemia in the Postanesthesia Care Unit Following Thoracoscopic Lung Surgery: A Multicenter Cohort Study. J Cardiothorac Vasc Anesth. Published 21 September 2025. doi:10.
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