Hemodynamics, fluids & transfusion

Development of an optimal maximum surgical blood ordering schedule to achieve a prespecified crossmatch-to-transfusion ratio

J Clin AnesthPublished Retrospective modelling study

Authors' conclusion

Our methodology provides an automated, optimal MSBOS for hospital blood bank inventory management that minimizes the probability that a patient will need a red blood cell transfusion that exceeds the reserved units, subject to the desired overall crossmatch to transfusion ratio.

Study context

Population
Adult surgical cases across 2430 procedure codes over 7.8 years at a teaching hospital2,430 procedure codes
Participants
192,822 cases
Exposure
Priority-based vs Mean-units heuristic
Outcome
Total hospital blood bank RBC units transfused but unreserved, optimal (priority-based) MSBOS with overall CT ratio ≤2.00
Methodological detailssingle-centre, algorithm development
  • Single-centre
  • Algorithm development

Main finding

As reported in the abstract

Decrease in total hospital blood bank units (surgical and non-surgical) transfused but unreserved, while maintaining the ≤2.00 crossmatch-to-transfusion (CT) ratio

37.9%

CT ratio across the 135 categories with ≥1 crossmatched unit, mean (SD)

1.787

0.977

Observational data: associations, not effects.

Original publication

Development of an optimal maximum surgical blood ordering schedule to achieve a prespecified crossmatch-to-transfusion ratio. J Clin Anesth. Published 19 April 2026. doi:10.1016/j.jclinane.2026.112203

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