Hemodynamics, fluids & transfusion

Differences in incidence of post-induction hypotension depending on the time of day: a post-hoc propensity score matched analysis

J Clin AnesthPublished Post-hoc propensity-score matched analysis of a prospective cohort

Primary resultResult — go to the resultOdds ratio 1.48 95 % CI 1.00–2.20

Authors' conclusion

Post-induction hypotension was more frequent in the morning compared to the afternoon.

Study context

Population
Elective non-cardiac surgery patients receiving GA
Participants
760 patients · 237 matched pairs
Comparison
Anaesthesia induction in the morning vs afternoon
Primary endpoint
Post-induction hypotension (MAP < 65 mmHg for at least one minute)

Primary result

As reported in the abstract

Odds ratio

1.48

95 % CI 1.00–2.20

P = 0.049

Morning vs Afternoon
OR 1.48 (95 % CI 1.00–2.20); P = 0.049

Secondary outcomes

OutcomeOR (95 % CI)P value
> 30 % decrease in MAPMatched cohort1.45 (1.00–2.11)P = 0.0499

Instantaneous baroreflex sensitivity

No differences observed

Original publication

Differences in incidence of post-induction hypotension depending on the time of day: a post-hoc propensity score matched analysis. J Clin Anesth. Published 3 September 2025. doi:10.1016/j.jclinane.2025.111984

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