Cardiothoracic & vascular anesthesia

Afternoon Anesthesia Induction is Associated with Post-Induction Hypotension in Patients Undergoing Off-Pump Coronary Artery Bypass Grafting: A Retrospective, Single-Centre Study Using Propensity Score Matching

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Authors' conclusion

This study is the first to report an association that afternoon anesthesia induction is an independent risk factor for PIH in patients undergoing OPCAB.

Study context

Population
Patients undergoing off-pump CABG (OPCAB), university hospital, October 2024–April 2025
Participants
934 patients · 360 matched pairs
Exposure
Afternoon vs morning anaesthesia induction
Methodological detailspropensity-score matched, single-centre
  • Propensity-score matched
  • Single-centre

Main finding

As reported in the abstract

Afternoon vs MorningEstimate (95% CI)P value
Unadjusted
OR 2.08(1.54–2.81)
P < 0.001
Adjusted
aOR 2.38(1.65–3.43)

Observational data: associations, not effects.

Further findings

5-variable nomogram for postinduction hypotension (PIH)

AUC/C-index, training set
0.737
AUC/C-index, testing set
0.738

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Afternoon Anesthesia Induction is Associated with Post-Induction Hypotension in Patients Undergoing Off-Pump Coronary Artery Bypass Grafting: A Retrospective, Single-Centre Study Using Propensity Score Matching. J Cardiothorac Vasc Anesth. Published 9 May 2026. doi:10.1053/j.jvca.2026.05.025

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