ICU sedation, delirium & recovery
Differences in intensive care outcomes between older adults with and without dementia: A systematic review and meta-analysis
Authors' conclusion
Older adults with dementia admitted to ICUs experience similar ICU mortality but higher long-term mortality, more delirium, and lower odds of mechanical ventilation.
Study context
- Population
- Older adults admitted to the intensive care unit (ICU); cohort studies 2003–2023 from six countries
- Participants
- 1,738,285 adults · 15 studies
- Comparison
- Older adults with vs without dementia
- Dementian = 173,107
- Outcome
- ICU mortality
Methodological detailsrandom-effects
- Random-effects
Pooled result
As reported in the abstract
- No difference in ICU mortality
- Adjusted analyses
Further pooled results
| Outcome | OR (95% CI) | |
|---|---|---|
| Deliriumn = 1 study | 4.80 (1.81–12.72) | |
| 0.050.21520Odds ratio (log scale) |
Safety
| Outcome | OR (95% CI) | |
|---|---|---|
| Deliriumn = 1 | 4.80 (1.81–12.72) | |
| 0.050.21520Odds ratio (log scale) |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Differences in intensive care outcomes between older adults with and without dementia: A systematic review and meta-analysis. J Crit Care. Published 1 April 2026. doi:10.
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