Respiratory failure & ventilation

Different ventilation intensities among various categories of patients ventilated for reasons other than ARDS––A pooled analysis of 4 observational studies

J Crit CarePublished Pooled individual patient data analysis of 4 observational studies

Authors' conclusion

The intensity of ventilation differed between patients with sepsis or pneumonia and patients receiving ventilation for any other reason; ΔP was associated with higher mortality in sepsis and pneumonia patients.

Study context

Population
Critically ill patients invasively ventilated for reasons other than ARDS4 observational studies
Participants
372 / 944 / 2,040
Comparison
Sepsis vs pneumonia vs neither
  • Sepsisn = 372
  • Pneumonian = 944
  • Othern = 2,040reference
Outcome
ΔP
Methodological detailspost hoc analysis
  • Post hoc analysis

Pooled result

As reported in the abstract

Day 1

Sepsis

14

median · IQR 11–18 · cmH2O

Pneumonia

14

median · IQR 11–18 · cmH2O

Other

13

median · IQR 10–16 · cmH2O

P < 0.001

Further pooled results

Mechanical power (MP)

Median MP also higher in sepsis and pneumonia patients

ICU mortality

ΔP, as opposed to MP, associated with ICU mortality in sepsis and pneumonia patients

Original publication

Different ventilation intensities among various categories of patients ventilated for reasons other than ARDS––A pooled analysis of 4 observational studies. J Crit Care. Published 10 February 2024. doi:10.1016/j.jcrc.2024.154531

Composed by AI from the published abstract and checked against it. How Briefs are made →

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