Neuroanesthesia & neurocritical care
Discrepancies in the late auditory potentials of post-anoxic patients: Watch out for focal brain lesions, a pilot retrospective study
Authors' conclusion
This study suggests that discrepancies in late auditory evoked potentials may be linked to focal post-anoxic brain lesions, visible on brain MRI.
Study context
- Population
- Post-anoxic disorders of consciousness patients
- Participants
- 38 participants
- Exposure
- Late auditory evoked potential profiles vs brain lesions on MRI
- MMN-/P3+n = 8
- MMN+/P3+n = 7
- MMN-/P3-n = 21
- MMN-/P3+n = 2
- Outcome
- Temporal and basal ganglia lesions on 3T MRI
Methodological detailspilot
- Pilot
Main finding
As reported in the abstract
- MMN-/P3+ tended to have fewer temporal and basal ganglia lesions than MMN-/P3-, and more than MMN+/P3+; p for trend, temporal
- p = 0.02
- p for trend, basal ganglia lesions
- p = 0.02
- Difference across groups in mean arcuate fasciculus fractional anisotropy
- p = 0.008
Observational data: associations, not effects.
Further findings
Regaining consciousness · 3 months
- Higher in MMN-/P3+ than MMN-/P3-, lower than MMN+/P3+
Original publication
Discrepancies in the late auditory potentials of post-anoxic patients: Watch out for focal brain lesions, a pilot retrospective study. Resuscitation. Published 20 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →