Does capnography improve safety in moderate-deep sedation for gastrointestinal endoscopic procedures provided by anaesthesiologists? A prospective cohort study
Authors' conclusion
Moderate-deep sedation for GEP performed by experienced anaesthesiologists, combined with capnography, enhances safety, with extremely rare major complications.
Study context
- Population
- Patients undergoing gastrointestinal endoscopic procedures under procedural sedation and analgesia (PSA) provided by experienced anaesthesiologists
- Participants
- 1,146 patients
- Exposure
- Capnography plus pulse oximetry vs pulse oximetry alone during PSA
- Pulse oximetryn = 538reference
- Capnographyn = 608
- Outcome
- Incidence of respiratory and cardiovascular adverse events
Main finding
As reported in the abstract
Moderate hypoxaemia
P = 0.004
Observational data: associations, not effects.
Further findings
Apnoea <60 s
- Detected only in patients monitored with capnography (capnography vs pulse oximetry)
- 35.4% vs. 0%, p < 0.000
Severe hypoxaemia (pts with cardio-respiratory comorbidities, subgroup)
- Significantly reduced with capnography only in pts with cardio-respiratory comorbidities
- 2.2% vs. 4.4%, p = 0.032
Cardiovascular events
- Lower incidence in the capnography group
Mandibular traction manoeuvres
- Significantly more frequent in Group B (capnography) vs Group A (pulse oximetry), reducing the need for other interventions
- 9.9% vs. 3%, p < 0.000
Patient satisfaction at discharge
- Higher when capnography was used
- P < 0,000
Safety
Prolonged apnoea and intubation
- Rare in both groups
Original publication
Does capnography improve safety in moderate-deep sedation for gastrointestinal endoscopic procedures provided by anaesthesiologists? A prospective cohort study. J Clin Monit Comput. Published 26 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →