Anesthetic drugs & techniques

Thoracic impedance pneumography in propofol-sedated patients undergoing percutaneous endoscopic gastrostomy (PEG) placement in gastrointestinal endoscopy: A prospective, randomized trial

J Clin AnesthPublished Randomised controlled trial

Primary result · Hypoxic episodesResult — go to the resultOdds ratio 0.47

Authors' conclusion

Additional thoracic impedance pneumography reduced the quantity and extent of hypoxic events with less need of assisted ventilation.

Study context

Population
Patients undergoing PEG placement under propofol sedation by gastroenterologists or trained nurses; mostly oncological indication, ASA II–III
Participants
173 patients
Comparison
Additional thoracic impedance pneumography vs standard monitoring
Primary endpoint
Hypoxic episodes (SpO2 < 90% for >15 s)
Methodological detailssingle-centre
  • Single-centre

Primary result

Hypoxic episodes

Odds ratio

0.47

P = 0.016

By group

As reported in the abstract

Secondary outcomes

Apnea >10s detected

P < 0.001

Apnea >30s detected

P = 0.014

Assisted ventilation needed

P = 0.053

OutcomeTIMSMP value
Minimal SpO2 per procedure90.0% ± 8.984.0% ± 17.6P = 0.007
Adjustments of oxygen flowSignificantly more often necessary in SMP = 0.034
Apnea >30s detected — Time advantage before hypoxic events
17 s

Additional cost of thoracic impedance pneumography per procedure

Calculated cost per procedure
0.13$ (0.12 €/0.11 £)

Original publication

Thoracic impedance pneumography in propofol-sedated patients undergoing percutaneous endoscopic gastrostomy (PEG) placement in gastrointestinal endoscopy: A prospective, randomized trial. J Clin Anesth. Published 17 February 2024. doi:10.1016/j.jclinane.2024.111403

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