Duration of analgesia after supraclavicular brachial plexus block with intravenous dexamethasone with or without dexmedetomidine: a randomised, placebo-controlled, triple-blind trial
Authors' conclusion
The combination of i.v. dexamethasone and dexmedetomidine does not provide superior analgesia than i.v. dexamethasone alone after supraclavicular brachial plexus block.
Study context
- Population
- Patients undergoing upper limb surgery with a supraclavicular brachial plexus blockrandomised
- Participants
- 100 patients
- Comparison
- Dexa-Dexme vs Dexa
- Primary endpoint
- Duration of analgesia from block (mepivacaine 0.5% + ropivacaine 0.25%) to first oral opioid intake
Methodological detailstriple-blind, placebo-controlled
- Triple-blind
- Placebo-controlled
Primary result
As reported in the abstract
P = 0.47
Secondary outcomes
Sensory and motor block duration, pain scores at rest and on movement, cumulative oral morphine consumption at 48 h
- No significant differences in the secondary outcomes
Original publication
Duration of analgesia after supraclavicular brachial plexus block with intravenous dexamethasone with or without dexmedetomidine: a randomised, placebo-controlled, triple-blind trial. Br J Anaesth. Published 1 December 2025. doi:10.
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