Respiratory failure & ventilation

Dynamic relative regional lung strain estimated by computed tomography and electrical impedance tomography in ARDS patients

Crit CarePublished Diagnostic accuracy study

Authors' conclusion

Changes in DRRS during a PEEP trial in ARDS patients could be monitored using EIT, based on changes in ΔZmL/EELIml and ∆ZAU.

Study context

Population
ARDS patients undergoing computed tomography (CT) and electrical impedance tomography (EIT) at low PEEP (ARDS-net) and high PEEP (EIT-titrated)
Participants
14 patients
Comparison
Three EIT-based methods for dynamic relative regional strain (DRRS) vs CT-based relative strain, between low and high PEEP
Outcome
Agreement of EIT-based DRRS with CT-based strain in non-dependent and dependent lung regions (linear regression, bias, limits of agreement)

Performance

As reported in the abstract

Relationship and agreement of EIT-based DRRS with CT
Test or modelR2, non-dependent regionR2, dependent regionR2, both regionsBias, non-dependent regionBias, dependent regionLimits of agreement, non-dependent regionLimits of agreement, dependent region
ΔZml/EELIml0.90500.8373
∆ZAU0.86790.6588
ΔZAU/EELIAU≈0.33.112.08- 2.13 to 8.34- 1.49 to 5.64

R2, non-dependent region

ΔZml/EELIml0.9050
∆ZAU0.8679
ΔZAU/EELIAU— not stated in the abstract

R2, dependent region

ΔZml/EELIml0.8373
∆ZAU0.6588
ΔZAU/EELIAU— not stated in the abstract

R2, both regions

ΔZml/EELIml— not stated in the abstract
∆ZAU— not stated in the abstract
ΔZAU/EELIAU≈0.3

Bias, non-dependent region

ΔZml/EELIml— not stated in the abstract
∆ZAU— not stated in the abstract
ΔZAU/EELIAU3.11

Bias, dependent region

ΔZml/EELIml— not stated in the abstract
∆ZAU— not stated in the abstract
ΔZAU/EELIAU2.08

Limits of agreement, non-dependent region

ΔZml/EELIml— not stated in the abstract
∆ZAU— not stated in the abstract
ΔZAU/EELIAU- 2.13 to 8.34

Limits of agreement, dependent region

ΔZml/EELIml— not stated in the abstract
∆ZAU— not stated in the abstract
ΔZAU/EELIAU- 1.49 to 5.64
ΔZml/EELIml and ∆ZAU: good relationship and agreement with CT; biases ranging (both methods, both regions)
- 0.11 to 0.51
ΔZml/EELIml and ∆ZAU: limits of agreement ranging (both methods, both regions)
- 0.73 to 1.16

Original publication

Dynamic relative regional lung strain estimated by computed tomography and electrical impedance tomography in ARDS patients. Crit Care. Published 24 November 2023. doi:10.1186/s13054-023-04748-4

Composed by AI from the published abstract and checked against it. How Briefs are made →

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