Respiratory failure & ventilation
Dynamic relative regional lung strain estimated by computed tomography and electrical impedance tomography in ARDS patients
Authors' conclusion
Changes in DRRS during a PEEP trial in ARDS patients could be monitored using EIT, based on changes in ΔZmL/EELIml and ∆ZAU.
Study context
- Population
- ARDS patients undergoing computed tomography (CT) and electrical impedance tomography (EIT) at low PEEP (ARDS-net) and high PEEP (EIT-titrated)
- Participants
- 14 patients
- Comparison
- Three EIT-based methods for dynamic relative regional strain (DRRS) vs CT-based relative strain, between low and high PEEP
- Outcome
- Agreement of EIT-based DRRS with CT-based strain in non-dependent and dependent lung regions (linear regression, bias, limits of agreement)
Performance
As reported in the abstract
Relationship and agreement of EIT-based DRRS with CT
| Test or model | R2, non-dependent region | R2, dependent region | R2, both regions | Bias, non-dependent region | Bias, dependent region | Limits of agreement, non-dependent region | Limits of agreement, dependent region |
|---|---|---|---|---|---|---|---|
| ΔZml/EELIml | 0.9050 | 0.8373 | |||||
| ∆ZAU | 0.8679 | 0.6588 | |||||
| ΔZAU/EELIAU | ≈0.3 | 3.11 | 2.08 | - 2.13 to 8.34 | - 1.49 to 5.64 |
R2, non-dependent region
ΔZml/EELIml0.9050
∆ZAU0.8679
ΔZAU/EELIAU— not stated in the abstract
R2, dependent region
ΔZml/EELIml0.8373
∆ZAU0.6588
ΔZAU/EELIAU— not stated in the abstract
R2, both regions
ΔZml/EELIml— not stated in the abstract
∆ZAU— not stated in the abstract
ΔZAU/EELIAU≈0.3
Bias, non-dependent region
ΔZml/EELIml— not stated in the abstract
∆ZAU— not stated in the abstract
ΔZAU/EELIAU3.11
Bias, dependent region
ΔZml/EELIml— not stated in the abstract
∆ZAU— not stated in the abstract
ΔZAU/EELIAU2.08
Limits of agreement, non-dependent region
ΔZml/EELIml— not stated in the abstract
∆ZAU— not stated in the abstract
ΔZAU/EELIAU- 2.13 to 8.34
Limits of agreement, dependent region
ΔZml/EELIml— not stated in the abstract
∆ZAU— not stated in the abstract
ΔZAU/EELIAU- 1.49 to 5.64
- ΔZml/EELIml and ∆ZAU: good relationship and agreement with CT; biases ranging (both methods, both regions)
- - 0.11 to 0.51
- ΔZml/EELIml and ∆ZAU: limits of agreement ranging (both methods, both regions)
- - 0.73 to 1.16
Original publication
Dynamic relative regional lung strain estimated by computed tomography and electrical impedance tomography in ARDS patients. Crit Care. Published 24 November 2023. doi:10. 1186/ s13054-023-04748-4
Composed by AI from the published abstract and checked against it. How Briefs are made →