Pediatric anesthesia & critical care
Early predictors of unfavorable outcomes in pediatric acute respiratory failure
Authors' conclusion
A significant proportion of pediatric patients with acute respiratory failure experienced unfavorable outcomes
Study context
- Population
- Children under 20 years admitted with acute respiratory diseases (July 2010–March 2022) receiving ventilatory support within the first 3 days of hospitalization, Japanese acute care hospitals
- Participants
- 29,362 eligible children
- Outcome
- Composite unfavorable outcomes
Methodological detailsnational inpatient database
- National inpatient database
Main finding
As reported in the abstract
Unfavorable outcomes
2663
9.1%
In-hospital death
669
2.3%
Discharged with new comorbidities
1994
6.8%
Observational data: associations, not effects.
Further findings
Predictors of unfavorable outcomes (logistic regression)
- Older age, underlying conditions, pneumonia and low hospital volume associated with unfavorable outcomes after adjustment
- Adjusted for covariates
Highest ventilatory support within first 3 days
- Invasive ventilation
- 69.4%
- NIV
- 1.0%
- HFNC
- 29.7%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Early predictors of unfavorable outcomes in pediatric acute respiratory failure. J Intensive Care. Published 2 December 2024. doi:10. 1186/ s40560-024-00763-x
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