Cardiothoracic & vascular anesthesia
Early Surgery for Infective Endocarditis Complicated With Neurologic Injury
Main finding · 30-day postoperative mortality (patients with preoperative neurologic complications)Result — go to the resultHazard ratio 0.21 95% CI 0.07–0.67Authors' conclusion
Early cardiac surgery may be associated with more favorable clinical outcomes in patients with preoperative neurologic complications.
Study context
- Population
- Patients with active left-sided infective endocarditis who underwent valve surgery, Chang Gung Research Database (7 hospitals, Taiwan), 2002–2018
- Participants
- 392 patients
- Exposure
- Early surgery vs Later surgery
- Outcome
- 30-day postoperative mortality (patients with preoperative neurologic complications)
- Follow-up
- 30 days
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Hazard ratio
0.21
95% CI 0.07–0.67
By group
Early surgery vs Later surgery
HR 0.21 (95% CI 0.07–0.67)
Observational data: associations, not effects.
Further findings
Postoperative stroke, in-hospital mortality, follow-up outcomes: with vs without neurologic complications
- No significant differences between patients with and without neurologic complications
In-hospital and post-discharge outcomes: brain ischemia vs hemorrhage (subgroup)
- No significant between-group difference
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Early Surgery for Infective Endocarditis Complicated With Neurologic Injury. J Cardiothorac Vasc Anesth. Published 15 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →