Respiratory failure & ventilation

Echocardiographic assessment of left ventricular filling pressure compared to pulmonary artery catheter in mechanically ventilated patients: Systematic review and meta-analysis

Ann Intensive CarePublished Systematic review and meta-analysis of prospective diagnostic studies

Authors' conclusion

Doppler echocardiography shows potential for assessing LVFP in critically ill patients on mechanical ventilation.

Study context

Population
Critically ill mechanically ventilated intensive care unit (ICU) patients
Participants
696 participants · 18 prospective studies
Comparison
Doppler echocardiography vs pulmonary artery occlusion pressure (PAOP) via pulmonary artery catheter
Outcome
Accuracy of echocardiographic measurements and their correlation with PAOP
Methodological detailsGRADE assessment
  • GRADE assessment

Pooled result

As reported in the abstract

Prediction of PAOP ≥ 18 mmHg and correlation with PAOP
GroupArea under the receiver operating characteristic (AUROC) rangePooled correlation coefficient
E/A0.69 to 0.830.48 (95% CI: 0.48-0.58)
Lateral E/E'0.60 to 0.910.72 (95% CI: 0.52-0.92)

Area under the receiver operating characteristic (AUROC) range

E/A0.69 to 0.83
Lateral E/E'0.60 to 0.91

Pooled correlation coefficient

E/A0.48 (95% CI: 0.48-0.58)
Lateral E/E'0.72 (95% CI: 0.52-0.92)

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Echocardiographic assessment of left ventricular filling pressure compared to pulmonary artery catheter in mechanically ventilated patients: Systematic review and meta-analysis. Ann Intensive Care. Published 16 January 2026. doi:10.1016/j.aicoj.2025.100024

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