Hemodynamics, fluids & transfusion
Echocardiographic assessment of pulmonary capillary wedge pressure by E/e' ratio: A systematic review and meta-analysis
Authors' conclusion
E/e' appears to have a modest correlation with PCWP and an acceptable accuracy for elevated PCWP.
Study context
- Population
- Adults in studies investigating agreement between E/e' and pulmonary capillary wedge pressure (PCWP), published 2010 to July 2022 (retrospective studies excluded)
- Participants
- 1,964 adults · 28 studies
- Comparison
- E/e' ratio vs invasive PCWP
- Outcome
- Correlation between E/e' and PCWP
Pooled result
As reported in the abstract
Weighted average correlation (r), pooled analysis: modest correlation between E/e' and PCWP
0.43
95% CI 0.37–0.48
Further pooled results
Correlation by ejection fraction (subgroup: reduced vs preserved EF)
- No significant differences between reduced and preserved ejection fraction groups
Diagnostic accuracy of E/e' for elevated PCWP (PCWP >15 mmHg)
- AUC of ROC curves for PCWP >15 mmHg, range
- 0.6-0.91
- 13 studies
Original publication
Echocardiographic assessment of pulmonary capillary wedge pressure by E/e' ratio: A systematic review and meta-analysis. J Crit Care. Published 1 March 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →