Cardiothoracic & vascular anaesthesia
The Association of the Systemic Oxygen Delivery to Oxygen Consumption Ratio With Mortality, Heart Transplantation, and Mechanical Circulatory Support
Authors' conclusion
A categorical threshold of 5 did not show an association with clinical outcomes, but continuous analyses did suggest that a low DO₂/VO₂ may identify a high-risk phenotype.
Study context
- Population
- Adults in medical and surgical cardiac ICUs (Mayo Clinic) with invasive hemodynamic assessment, January 2012–December 2025; sepsis/septic shock excluded
- Exposure
- DO2/VO2 ratio as continuous measure and at a prespecified cut-point of 5
- Outcome
- Mortality
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Nonlinear association of DO2/VO2 with mortality; highest likelihood of mortality at DO2/VO2 ∼2 (reference: median 4.73)
- No significant relationship with mortality at prespecified cut-point of 5 (Kaplan-Meier)
- No significant association with need for mechanical circulatory support or heart transplantation
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
The Association of the Systemic Oxygen Delivery to Oxygen Consumption Ratio With Mortality, Heart Transplantation, and Mechanical Circulatory Support. J Cardiothorac Vasc Anesth. Published 24 September 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →