Cardiothoracic & vascular anaesthesia
Global Longitudinal Strain as a Predictor of Challenging Separation from Cardiopulmonary Bypass
Authors' conclusion
Fully automated, operator-independent preoperative GLS was strongly and independently associated with challenging separation from CPB, with a clinically applicable threshold.
Study context
- Population
- Adults undergoing cardiac surgery with cardiopulmonary bypass (CPB), adequate preoperative transthoracic echocardiographic windows; excluded preoperative AF, inotropic/mechanical circulatory support or mechanical ventilationconsecutive
- Participants
- 52 adults
- Exposure
- Challenging vs easy CPB separation
- Outcome
- Challenging separation from CPB (easy vs challenging), predicted by preoperative global longitudinal strain (GLS)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Preoperative GLS
Challenging weaning
−11.8%
IQR −14.0%–-10.3%
Easy-weaning
−16.1%
IQR −18.6%–-15.4%
GLSOdds ratio (95% CI)P value
Multivariable, adjusted for EuroSCORE II, LV ejection fraction category, CPB duration, type of surgery; only independent predictor
1.40(1.09–1.79)
P < 0.01- Threshold −14.0%: sensitivity 80.0%, specificity 90.9%
- AUC 0.864 (95% CI 0.740–0.969); P < 0.001
Observational data: associations, not effects.
Further findings
CPB time
P = 0.036
| Outcome | Challenging weaning | Easy-weaning | P value |
|---|---|---|---|
| Aortic cross-clamp time | 89.0 (range 67.5–116.0) | 61.0 (range 40.0–79.0) | P = 0.004 |
Original publication
Global Longitudinal Strain as a Predictor of Challenging Separation from Cardiopulmonary Bypass. J Cardiothorac Vasc Anesth. Published 23 September 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →