Cardiac arrest & resuscitation
Echocardiography findings in amniotic fluid embolism: a systematic review of the literature
Authors' conclusion
Right ventricular dysfunction on echocardiography is a common finding in AFE and is associated with a high risk of cardiac arrest.
Study context
- Population
- Patients with amniotic fluid embolism (AFE) (meeting at least one of three proposed AFE criteria) with echocardiography findings during hospitalization80 publications
- Participants
- 84 patients
- Outcome
- Echocardiography findings
Methodological detailsunivariate logistic regression, Joanna Briggs Institute appraisal tool for case series, Low risk of bias in 15/84 (18%) cases
- Univariate logistic regression
- Joanna Briggs Institute appraisal tool for case series
- Low risk of bias in 15/84 (18%) cases
Pooled result
As reported in the abstract
Right ventricular (RV) dysfunction
55 of 82
67%
Biventricular dysfunction (included in RV dysfunction)
11 of 82
13%
Normal systolic function
14 of 82
17%
No RV or left ventricular function data
2
Further pooled results
Association of RV dysfunction with cardiac arrest
| OR (95% CI) | P value | ||
|---|---|---|---|
| RV dysfunction | 3.66 (1.39–9.67) | P = 0.009 | |
| 0.10.31310Odds ratio (log scale) |
Association of RV dysfunction with composite of cardiac arrest, maternal death or ECMO use
| OR (95% CI) | P value | ||
|---|---|---|---|
| RV dysfunction | 3.86 (1.43–10.4) | P = 0.007 | |
| 0.050.21520Odds ratio (log scale) |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Echocardiography findings in amniotic fluid embolism: a systematic review of the literature. Can J Anaesth. Published 28 October 2022. doi:10.
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