Education or sedation? A randomized clinical trial of impact on procedural pain and satisfaction during regional block placement, and the moderating effect of pain catastrophizing
Primary result · Maximal procedural pain immediately after the procedureResult — go to the resultTreatment×PCS group interaction (B) 0.8 95% CI 0.04–1.5Authors' conclusion
Our findings suggest that patients with high PCS may disproportionately benefit from sedation during nerve block, reporting less pain, whereas patients with low PCS may have a slight preference for education/reassurance, reporting higher satisfaction.
Study context
- Population
- Patients undergoing preoperative peripheral nerve block placement, stratified into low-PCS (<10) or high-PCS (≥10)
- Participants
- 72 patients
- Comparison
- Sedation vs education/reassurance during nerve block placement
- Primary endpoint
- Maximum procedural pain
- Follow-up
- Immediately after the procedure
Methodological detailsstratified by baseline Pain Catastrophizing Scale (PCS)
- Stratified by baseline PCS
Primary result
As reported in the abstract
Maximal procedural pain immediately after the procedure
Treatment × PCS group interaction (B)
0.8
95% CI 0.04–1.5
P = 0.04
Further findings
| Outcome | Sedation | Education/reassurance | P value |
|---|---|---|---|
| Maximal procedural pain, high-PCS subgroup · immediately after the procedure | 2.3 (SD 2.2) | 4.3 (SD 2.5) | P = 0.01 |
| Recalled procedural pain in PACUExploratory | 0.3 (SD 0.7) | 2.2 (SD 2.4) | P < 0.001 |
Satisfaction, low-PCS subgroup
- Education associated with higher satisfaction among those with lower PCS
- Exploratory
Original publication
Education or sedation? A randomized clinical trial of impact on procedural pain and satisfaction during regional block placement, and the moderating effect of pain catastrophizing. Reg Anesth Pain Med. Published 5 June 2025. doi:10.
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