Neuroanesthesia & neurocritical care
Effect of Extracerebral Contamination on Near-infrared Spectroscopy as Revealed during Organ Donation: A Prospective Observational Study in Brain-dead Organ Donors
Authors' conclusion
The abrupt end of extracerebral contamination, caused by aortic clamping, affected both NIRS monitors to a considerable extent. Both the INVOS and the ForeSight monitor were unable to detect severe cerebral hypoxia or anoxia under conditions of normal extracerebral oxygenation.
Study context
- Population
- Brain-dead adults undergoing organ donation, rScO2 measured bifrontally
- Participants
- 12 organ donors
- Exposure
- INVOS vs ForeSight near-infrared spectroscopy (NIRS) monitor
- Outcome
- Extracerebral contamination quantified by the absolute decrease in rScO2 after aortic clamping
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Absolute decrease in rScO2 after aortic clamping
P < 0.001
Observational data: associations, not effects.
Secondary outcomes
rScO2 before aortic clamping · near-normal values
rScO2 after aortic clamping · 30 min after clamping
- rScO2 after aortic clamping — rScO2 significantly dropped after clamping
- P < 0.001
Original publication
Effect of Extracerebral Contamination on Near-infrared Spectroscopy as Revealed during Organ Donation: A Prospective Observational Study in Brain-dead Organ Donors. Anesthesiology. Published 8 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →