Cardiac arrest & resuscitation
Effect of intra-arrest transport, extracorporeal cardiopulmonary resuscitation and immediate invasive assessment in refractory out-of-hospital cardiac arrest: a long-term follow-up of the Prague out-of-hospital cardiac arrest (OHCA) trial
Authors' conclusion
Among patients with refractory OHCA, the ECPR-based approach significantly improved long-term survival.
Study context
- Population
- Patients with witnessed refractory OHCA of presumed cardiac origin, without ROSC, randomised on scene during ongoing resuscitation255 completed follow-up
- Participants
- 256 patients
- Comparison
- Extracorporeal cardiopulmonary resuscitation (ECPR)-based approach vs conventional CPR
- ECPR-basedn = 123
- Conventional CPR (CCPR)n = 132reference
- Primary endpoint
- Long-term survival
- Follow-up
- 5.3 (IQR 3.8-7.2) years after randomisation
Methodological detailssingle-center, open-label
- Single-center
- Open-label
Primary result
As reported in the abstract
Alive at long-term follow-up
P = 0.01
Further findings
Poor neurological outcome among long-term survivors (CPC 3)
Neurological outcome, survival after hospital discharge, hospitalization, major cardiovascular events, quality of life
- No significant differences between groups
Original publication
Effect of intra-arrest transport, extracorporeal cardiopulmonary resuscitation and immediate invasive assessment in refractory out-of-hospital cardiac arrest: a long-term follow-up of the Prague OHCA trial. Crit Care. Published 16 April 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →