ICU sedation, delirium & recovery
Effect of linearly polarized light irradiation near stellate ganglion on postoperative sleep disorders in patients undergoing modified radical mastectomy of breast cancer
Authors' conclusion
LI-SG improved the postoperative sleep quality and analgesic effect of patients, while improving patient satisfaction.
Study context
- Population
- Patients undergoing modified radical mastectomy of breast cancer
- Participants
- 114 patients
- Comparison
- LI-SG vs control
- Primary endpoint
- Subjective sleep quality (Pittsburgh Sleep Quality Index, PSQI)
Methodological detailsprospective, Conducted June 2024 to December 2024
- Prospective
- Conducted June 2024 to December 2024
Primary result
As reported in the abstract
Subjective sleep quality (PSQI) · second and 5th postoperative day
- Pittsburgh Sleep Quality Index (PSQI) significantly improved in LI-SG vs control at the second and 5th postoperative day
- all P < 0.001
Secondary outcomes
| Outcome | LI-SG | Control | P value |
|---|---|---|---|
| VAS scoreSignificantly decreased in LI-SG | 2.51 ± 0.47 | 3.51 ± 0.77 | P < 0.001 |
| Total number of PCA compressionsSignificantly decreased in LI-SG | 5.62 ± 1.53 | 15.39 ± 2.11 | P < 0.001 |
| Patient satisfactionHigher in LI-SG | 6 | 4 | P < 0.001 |
Objective sleep measures (sleep efficiency, total sleep time, awakening times) · second and 5th postoperative day
- Significantly improved in LI-SG vs control at the second and 5th postoperative day
- all P < 0.001
Serum melatonin, TNF-α and IL-6 · second and 5th postoperative day
- Melatonin significantly increased, TNF-α and IL-6 decreased in LI-SG at the second and 5th postoperative day
- all P < 0.001
Safety
PONV · lower in LI-SG
P < 0.001
Original publication
Effect of linearly polarized light irradiation near stellate ganglion on postoperative sleep disorders in patients undergoing modified radical mastectomy of breast cancer. Perioper Med (Lond). Published 21 October 2025. doi:10.
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