Cardiothoracic & vascular anesthesia
Effects of short-term preoperative intranasal dexmedetomidine plus conventional treatment on delirium following cardiac surgery in patients with sleep disorders
Primary resultResult — go to the resultOdds ratio 0.318 95% CI 0.112–0.905Authors' conclusion
The combined treatment involving DEX demonstrated a decreased incidence of POD in elderly individuals with sleep disorders undergoing cardiac surgery compared to the placebo combination treatment.
Study context
- Population
- Patients aged ≥60 years with sleep disorders (Pittsburgh Sleep Quality Index ≥8) undergoing cardiac surgery at a university hospital
- Participants
- 100 patients
- Comparison
- Group B vs Group A
- Group Bn = 50
- Group An = 50reference
- Primary endpoint
- Postoperative delirium (POD) (Confusion Assessment Method for the ICU (CAM-ICU) in the cardiac surgery intensive care unit (CSICU); CAM on the ward)
Methodological detailsprospective, placebo-controlled
- Prospective
- Placebo-controlled
Primary result
As reported in the abstract
Odds ratio
0.318
95% CI 0.112–0.905
P = 0.027
By group
Group B vs Group A
OR 0.318 (95% CI 0.112–0.905); P = 0.027
Original publication
Effects of short-term preoperative intranasal dexmedetomidine plus conventional treatment on delirium following cardiac surgery in patients with sleep disorders. Perioper Med (Lond). Published 9 March 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →