Cardiothoracic & vascular anesthesia
Effect of Bicuspid or Tricuspid Aortic Valve on Preoperative Coagulation in Patients Scheduled for Thoracic Aortic Surgery
Authors' conclusion
Patients with a BAV have similar preoperative coagulation profiles and postoperative outcomes as TAV patients, based on ROTEM and conventional coagulation tests.
Study context
- Population
- Patients undergoing elective thoracic aortic surgery
- Participants
- 169 patients
- Exposure
- Bicuspid vs tricuspid aortic valve
- Bicuspid aortic valve (BAV)n = 63
- Tricuspid aortic valve (TAV)n = 106reference
- Outcome
- Preoperative ROTEM values and coagulation tests
Methodological detailsexploratory, single-centre
- Exploratory
- Single-centre
Main finding
As reported in the abstract
- No significant differences between groups, except higher D-dimers in TAV
- Sex a significant confounder; aortic diameter a significant mediator
Observational data: associations, not effects.
Further findings
Baseline characteristics
- BAV on average 10 years younger
- BAV median aortic diameter 5 mm smaller
RBC and platelet transfusions
- More RBC and platelet transfusions in TAV, likely due to more preoperative antiplatelet therapy and longer CPB times
Mortality and postoperative complications
- Similar between groups
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Effect of Bicuspid or Tricuspid Aortic Valve on Preoperative Coagulation in Patients Scheduled for Thoracic Aortic Surgery. J Cardiothorac Vasc Anesth. Published 22 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →