Cardiothoracic & vascular anesthesia
Effect of Mechanical Ventilation Mode Type on Postoperative Pulmonary Complications After Cardiac Surgery: A Randomized Controlled Trial
Authors' conclusion
Among patients scheduled for cardiac surgery with CPB, intraoperative ventilation mode type did not affect the risk of postoperative pulmonary complications.
Study context
- Population
- Adults undergoing cardiac surgery with cardiopulmonary bypass (CPB), all receiving lung-protective ventilation
- Participants
- 1,364 adults
- Comparison
- Volume-controlled ventilation (VCV) vs pressure-controlled ventilation (PCV) vs pressure-controlled ventilation-volume guaranteed (PCV-VG) during CPB cardiac surgery
- PCV-VGn = 455
- Primary endpoint
- Composite of PPCs
- Follow-up
- First 7 postoperative days
Methodological detailssingle-centre, prospective
- Single-centre
- Prospective
Primary result
As reported in the abstract
P = 0.585
Further findings
Severity grade of postoperative pulmonary complications (PPCs) within 7 days, postoperative ventilation duration, ICU stay, postoperative hospital stay, 30-day mortality
- No significant differences among groups
Original publication
Effect of Mechanical Ventilation Mode Type on Postoperative Pulmonary Complications After Cardiac Surgery: A Randomized Controlled Trial. J Cardiothorac Vasc Anesth. Published 19 November 2023. doi:10.
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