Cardiothoracic & vascular anesthesia

Effect of the Paravertebral Block on Chronic Postsurgical Pain After Thoracic Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

J Cardiothorac Vasc AnesthPublished Systematic review and meta-analysis of randomised trials

Authors' conclusion

Thoracic PVB does not prevent CPSP after thoracic surgery.

Study context

Population
Adults undergoing thoracic surgery
Participants
1,028 adults · 10 randomized controlled trials (RCTs)
Comparison
Thoracic paravertebral block (PVB) vs no block or other blocks
Outcome
Incidence of chronic postsurgical pain (CPSP)
Follow-up
3 months

Pooled result

As reported in the abstract

Odds ratio (95% CI)P value
PVB vs No blockI2 = 6.96%
0.59(0.34–1.04)
P = 0.07
PVB vs Other blockI2 = 77.75%
1.39(0.30–6.42)
P = 0.67

Further pooled results

OutcomeOR (95% CI)P value
Incidence of CPSP · 6 monthsPVB vs No block · I2 = 87.53%0.44 (0.08–2.53)P = 0.36
Incidence of CPSP · 6 monthsPVB vs Other block · I2 = 45.75%1.17 (0.71–1.95)P = 0.93

Postoperative pain at rest · 24 and 48 hours

PVB significantly decreased pain at rest at 24 and 48 h vs no block
Pain score higher with PVB than other blocks at rest at 48 h

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Effect of the Paravertebral Block on Chronic Postsurgical Pain After Thoracic Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Cardiothorac Vasc Anesth. Published 3 November 2022. doi:10.1053/j.jvca.2022.10.029

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