Cardiothoracic & vascular anesthesia
Effectiveness of Surgeon-Performed Paravertebral Block Analgesia for Minimally Invasive Thoracic Surgery: A Randomized Clinical Trial
Authors' conclusion
PVB placed by a surgeon during thoracoscopy was noninferior to PVB placed by an anesthesiologist using ultrasonography before incision in terms of opioid consumption during the first 48 hours.
Study context
- Population
- Adults undergoing scheduled minimally invasive (video-assisted or robotic) thoracic surgery with lung resection
- Participants
- 196 adults
- Comparison
- PVB-VATS vs PVB-US
- PVB-VATSn = 98
- PVB-USn = 98reference
- Primary endpoint
- Mean post-PVB opioid consumption (noninferiority range <7.5 mg between groups)
- Follow-up
- 48 hours
Methodological detailssingle-centre, non-inferiority, patient-blinded
- Single-centre
- Non-inferiority
- Patient-blinded
Primary result
As reported in the abstract
Difference
−5.4 mg
95% CI -∞ to −0.93
P ≤ 0.001
By group
PVB-VATS vs PVB-US
difference −5.4 mg (95% CI -∞ to −0.93); P ≤ 0.001
Secondary outcomes
Pain score at rest and while coughing; overall time
- Did not differ between groups
Safety
Postoperative complications
- Did not differ between groups
Original publication
Effectiveness of Surgeon-Performed Paravertebral Block Analgesia for Minimally Invasive Thoracic Surgery: A Randomized Clinical Trial. JAMA Surg. Published 1 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →