Cardiothoracic & vascular anesthesia
Continuous Intertransverse Process Block Versus Continuous Paravertebral Block for Postoperative Analgesia After Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial
Primary result · 48-hour morphine consumptionResult — go to the resultMean difference 1.0 mg 95% CI −0.39 to 2.45Authors' conclusion
Continuous ITPB resulted in similar 48-hour morphine consumption, pain scores, and complication rates to continuous PVB for VATS, together with a shorter time to perform the block. However, the non-inferiority of ITPB to PVB was not statistically confirmed.
Study context
- Population
- Adults undergoing elective video-assisted thoracoscopic surgery (VATS) at a university hospitalenrolled
- Participants
- 55 adults
- Comparison
- Continuous intertransverse process block (ITPB) vs continuous paravertebral block (PVB)
- ITPBn = 25
- PVBn = 25reference
- Primary endpoint
- Total morphine consumption
- Follow-up
- First 48 postoperative hours
Methodological detailsdouble-blind, non-inferiority, single-centre
- Double-blind
- Non-inferiority
- Single-centre
Primary result
48-hour morphine consumption · 48 hours
Mean difference
1.0 mg
95% CI −0.39 to 2.45
P = 0.151
By group
ITPB vs PVB
mean difference 1.0 mg (95% CI −0.39 to 2.45); P = 0.151
Non-inferiority margin 1 as printed, not drawn
As reported in the abstract
Secondary outcomes
Block performance time · shorter with ITPB
P < 0.001
Visual analog scale (VAS) at rest and with deep breathing · all time points
- Comparable at all time points
- P > 0.05 for all
Original publication
Continuous Intertransverse Process Block Versus Continuous Paravertebral Block for Postoperative Analgesia After Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial. J Cardiothorac Vasc Anesth. Published 3 August 2026. doi:10.
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