Perioperative medicine & outcomes

Effect of time of day on outcomes in elective surgery: a systematic review

AnaesthesiaPublished Systematic review

Pooled result · Mortality, evening/night-time vs daytimeResult — go to the resultOdds ratio 1.35 to 3.98 95% CI 1.16-1.56 to 1.54-10.30

Authors' conclusion

We found that evening/night-time elective surgery is associated with a higher risk of mortality compared with daytime surgery.

Study context

Population
Patients undergoing elective (not urgent or emergency) surgery19 retrospective cohorts, 1 prospective cohort, 1 RCT
Participants
798,914 patients
Comparison
Evening/night-time vs Daytime
Outcome
Mortality, morbidity and other clinical outcomes
Methodological detailsrisk of bias screening, Most studies low quality of evidence (retrospective, not all corrected for patient characteristics); heterogeneous time slots and outcomes
  • Risk of bias screening
  • Most studies low quality of evidence (retrospective, not all corrected for patient characteristics); heterogeneous time slots and outcomes

Pooled result

Mortality, evening/night-time vs daytime

Odds ratio

1.35 to 3.98

95% CI 1.16-1.56 to 1.54-10.30

As reported in the abstract

Further pooled results

Outcomes, morning vs afternoon surgery

No differences (four studies, n = 3277)

Original publication

Effect of time of day on outcomes in elective surgery: a systematic review. Anaesthesia. Published 7 August 2024. doi:10.1111/anae.16395

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